Program
Wednesday, September 25, 2024
RNA systems biology
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08:40 - 08:50 | Opening Remarks: Maria Carmo-Fonseca, Institute for Molecular Medicine (IMM), University of Lisbon
, Portugal - 08:50 - 09:30 | Keynote Lecture: Yoseph Barash, University of Pennsylvania, Philadelphia, PA, USA, "Finding where to target RNA for therapeutic intervention"
09:35 – 09:55
Manuel Irimia, Centre for Genomic Regulation, Barcelona, Spain
10:00 – 10:20
Katharina Höfer, Max Planck Institute for Terrestrial Microbiology, Marburg, Germany
- 10:20 - 10:50 Break
10:50 – 11:10
Mary A. O’Connell, Central European Institute of Technology (CEITEC), Brno, Czech Republic
11:15 – 11:35
Martin Akerman, Envisagenics Inc. New York, USA
Poster Teasers
11:40 – 12:00
- 12:00 – 13:00 Lunch
The Interplay of Transcription and Splicing
13:00 – 13:20
Maria Carmo-Fonseca, Institute for Molecular Medicine (IMM), University of Lisbon, Portugal
miRNA-Based Logic Circuits Encoded on Self-Amplifying RNA for Highly Specific Cancer Cell Classification
13:25 - 13:45
Ron Weiss, Massachusetts Institute of Technology, USA
Development of FTO inhibitors for mRNA stabilization to treat AML cancer
13:50 - 14:10
Amir Mor, RNAble, Ness Ziona, Israel
RNA therapeutics development
14:15-14:20
Opening Remarks: Rotem Karni, The Institute for Medical Research Israel-Canada, Hebrew University- Hadassah Medical School, Israel
Keynote Lecture | Antisense Therapy for Diffuse Midline Glioma
14:20 - 15:00
Adrian R. Krainer, Cold Spring Harbor Laboratory, New York, USA
15:05 - 15:25
Annemieke Aartsma-Rus, Leiden University, The Netherlands
- 15:30 - 16:00 Break
REM-422, a small molecule that reprograms RNA processing to target MYB-driven hematological and solid cancers
16:00 - 16:20
Silvia Buonamici, Remix Therapeutics, Watertown, MA, USA
Oral splicing-regulation therapy for genetic diseases and cancer
16:25 - 16:45
Masatoshi Hagiwara, MD & PhD, Professor & Chairman, Graduate School of Medicine, Department of Drug Discovery Medicine, Kyoto University, Japan
Neutrophil-specific mRNA delivery - shooting at a moving target
16:50 - 17:10
Zvika Granot, Faculty of Medicine, Hebrew University, Jerusalem, Israel
Panel Discussion: Turning Science into Solutions: The Power of the CanceRNA Consortium
17:15 - 18:45
Tamar Raz, CEO, Hadasit Medical Research Services and Development, Jerusalem, Israel
Thursday, September 26, 2024
RNA therapeutics development (cont.)
Splice-switching Antisense Oligonucleotide Drug Discovery for Rare Neurodegenerative Diseases
08:50 - 09:10
Michelle L. Hastings, University of Michigan, Ann Arbor, MI, USA
Modulating mRNA stability for genetic diseases and cancer therapy
09:15 - 09:35
Rotem Karni, The Institute for Medical Research Israel-Canada, Hebrew University- Hadassah Medical School, Israel
RNA splicing in cancer
- 09:40 – 09:45 | Opening Remarks: Juan Valcarcel, Center for Genomic Regulation, Barcelona, Spain
- 09:45 – 10:25 | Keynote Lecture: Marisol Soengas, PhD, Senior Scientist, Spanish National Cancer Research Centre (CNIO), Madrid, Spain, RNA splicing in cancer
- 10:30 - 10:50 Break
Building specificity of anti-tumor splicing inhibitors targeting SF3B1.
10:50 – 11:10
Juan Valcarcel, Centre for Genomic Regulation, Barcelona, Spain
11:15 – 11:35
Florian Heyd, Free University of Berlin, Germany
Alternative splicing of immune receptors as a regulatory mechanism
11:40 – 12:00
Michal Lotem, Hadassah Hebrew University Medical Center, Jerusalem, Israel
12:00 – 12:20
Niels Schaft, University of Erlangen, Erlangen, Germany
Poster Session
12:55 - 13:30
- 13:30 – 14:30 Lunch
14:30 - 14:50
Raul Mendez, Barcelona Institute for Research in Biomedicine, Barcelona, Spain
14:55 – 15:15
Evelien Smits, University of Antwerp, Belgium
- 15:20 – 15:50 | Break
A-to-I RNA editing in cancer
15:50 – 16:10
Erez Levanon, Bar Ilan University, Ramat Gan, Israel
Friday, September 27, 2024
CanceRNA Internal Meeting | RNA therapeutics
- 12:35 - 13:10 | Lunch & Farewell