Organizing Committee
Prof. Michal Lotem
The Founder and Head of the Hadassah Cancer Research Institute, Professor Michal Lotem is an international expert in skin cancer and clinical oncology, driving cutting-edge scientific innovation at the HCRI since its inception in 2019. Her vision for HCRI is to investigate the nature of various cancers and enable HRCI’s physicians, scientists and researchers to develop new and personalized ways to manipulate the immune system to cure cancer, with the goal of eradicating cancer.
Prof. Claudio Sette
Principal Investigator
Catholic University of the Sacred Heart, School of Medicine, Italy
Prof. Rotem Karni
Prof. Rotem Karni is an internationally recognized expert in RNA biology and cancer research. His work focuses on alternative splicing, RNA-binding proteins, and RNA-based therapeutic strategies in oncology. He holds joint appointments at the University of Pennsylvania and Hebrew University-Hadassah Medical School, where he leads a multidisciplinary lab investigating the molecular mechanisms of gene expression regulation in cancer. Prof. Karni’s discoveries have led to the development of innovative RNA-targeted therapies currently progressing toward clinical application
Dr. Ernesto Guccione
Dr. Guccione started his independent lab at A*STAR in Singapore in 2008 and since 2019 has been a Professor at Mount Sinai Icahn School of Medicine where he is the director of the Mount Sinai Center for OncoGenomics and Innovative Therapeutics (COGIT).
Dr. Guccione has a long-standing interest in understanding basic mechanisms of transcriptional and post-transcriptional (e.g. splcing) regulation in order to identify therapeutic opportunities in oncology.
In particular he focused his research on dissecting the role of oncogenic Protein Methyltransferases (PMTs), and on the design and testing of Antisense Oligonucleotides (ASOs).
